MOA (Mechanism of Action) videos provide a deeper understanding of molecular mechanisms by showcasing dynamic interactions that are otherwise invisible to the naked eye. Unlike traditional resources like text-based documents and static images, they bring intricate biological mechanisms to life with clear, dynamic animations. In this article, we introduce 3 types of MOA videos with 9 examples to help you see how they communicate essential information about the mechanisms of drug action.

Before we go deeper into each type of MOA video, check the video below to take a glance of what it is.

What are MOA Videos?

MOA videos, or Mechanism of Action videos, are often referred to as method of action or mode of action videos. They show how a drug functions at the molecular and cellular levels to produce its therapeutic effects. 

For example, an antibiotic’s MOA might describe how it stops bacteria from growing, while a pain reliever’s MOA explains how it blocks pain signals.

So, why videos of MOA are among the most effective tools to explain and educate medical scientific-based knowledge, here are the 5 reasons:

• Simplify complex and invisible biomedical processes: MOA videos clearly visualize intricate mechanisms inside our bodies like receptor-ligand interactions or signal transduction pathways and transform them into visually digestible formats, making advanced science accessible to all audiences.
• Maximize viewer engagement: Video content generates 1200% more shares than text and images combined. High-quality MOA animations, with precise molecular visuals, captivate audiences more effectively than static infographics.
• Enhance knowledge retention: Research indicates that combining audio and visual learning increases retention rates by up to 65%, making MOA videos a superior tool for training healthcare professionals or educating patients.
• Build scientific credibility: High-quality animations demonstrate pharmaceutical companies’ commitment to accuracy and innovation, reinforcing trust among medical experts, regulators, and patients.
• Inform critical decision-making: By vividly showcasing drug efficacy and mechanisms, MOA videos empower physicians with better prescribing confidence and aid patients in understanding treatment benefits.

Now, let’s watch a video of aspirin’s MOA to learn how MOA videos depict intricate processes inside our bodies.

3 Types of MOA Videos with 9 Examples

Given these advantages, let’s dive into the three main types of MOA videos: Whiteboard, 2D, and 3D, and examples of each type to see how they transform molecular mechanisms into stunning visuals. 

Type	Definition	Pros	Cons	When to Use
3D MOA Animated Videos	Uses hyper-realistic 3D graphics to depict molecular and cellular interactions in lifelike detail, making complex mechanisms visually accessible.	– High visual realism – Superior depth and perspective – Credibility for advanced topics	– High cost – Longer production time – Overwhelming for non-expert audiences	For advanced scientific audiences such as healthcare professionals or researchers; ideal for presenting intricate biological mechanisms requiring depth and precision.
2D MOA Animated Videos	Simplifies complex biological and medical processes into flat, vibrant visuals that focus on clarity and high-level overviews using creative storytelling and illustrative diagrams.	– Visually engaging – Clear and flexible storytelling – Customizable for branding	– Limited depth for intricate processes – Lacks realism	For audiences seeking simplified overviews of medical or scientific processes, such as patients or healthcare professionals requiring a broader understanding without excessive detail.
Whiteboard MOA Videos	Features hand-drawn visuals that mimic real-time sketching, paired with engaging voiceovers, to create approachable narratives explaining complex medical science.	– Cost-effective – Engaging and familiar format – Versatile for different audiences	– Limited complexity in visuals – Overuse may feel generic	For early-stage pharmaceutical communication or educating broad audiences, including patients or non-specialists, in a simple, approachable manner.

3D MOA animated videos

3D animated videos are a popular choice for MOA because they bring the microscopic world to life, making complex mechanisms visually accessible. By harnessing cutting-edge computer graphics, these videos deliver hyper-realistic depictions of molecular interactions, cellular activities, and biochemical processes. 

This unparalleled precision makes it a preferred choice in educating healthcare professionals about complex mechanisms, such as a drug’s selective targeting of diseased cells or its role in modulating signaling pathways.

To see this in action, here’s an example of a 3D MOA animation that illustrates the MOA of Oncology.

Pros:

• High visual realism: Provides lifelike, detailed depictions of complex processes, making them easier to imagine and understand.
• Superior depth and perspective: Allows viewers to see processes from multiple angles and zoom in on specific details.
• Credibility for advanced topics: Preferred by healthcare professionals and researchers for presenting scientific accuracy.

Cons:

• High cost: 3D animations require skilled professionals, advanced software, and significant production time, making them expensive.
• Longer production time: Due to the complexity and technical factors, 3D MOA animated videos often require a significant production time. The more intricate and realistic the design, the longer it takes to produce at every phase of the process.
• Overwhelm for non-experts: Excessive detail can make videos confusing for audiences without a strong scientific background.

Pro tip: Use visual cues like zoom-ins, labels, or slow motion to emphasize critical points in the mechanism. And to make the science digestible, you should avoid cramming too much detail into one scene.

Here are 3 informative 3D animated videos that delve into the mechanisms of medical treatments. Each video utilizes engaging visuals to enhance understanding of complex biological processes:

How monoclonal antibodies treat cancer

This video ​​provides a comprehensive overview of monoclonal antibodies and their mechanisms in cancer treatment. To support understanding, it uses 3D illustrations of proteins and cells to visualize complex biological processes, making it easier for viewers to understand how these therapies work at a molecular level.

Non-steroidal anti-inflammatory drug animation

https://www.youtube.com/watch?v=Jc7H1W2lKK4

The video below explains the mechanism of action of diclofenac, a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory conditions. Using high-quality scientific visuals, it depicts these biochemical processes clearly and helps enhance comprehension.

Insulin synthesis and mechanism of action

This is ​​a part of a series focused on diabetes mellitus produced by Moving Medical Media. It covers the process of insulin synthesis and explains how insulin interacts with receptors on target cells. One factor that makes it stand out is the use of distinct colors for different components (e.g., insulin, glucose, receptors), which aids in distinguishing between various elements in the biological processes.

2D MOA animated videos

2D MOA animated videos offer a powerful way to simplify intricate biological and medical processes with flat, vibrant visuals and engaging motion. These animations are expertly designed to provide a clear, high-level overview of how treatments, drugs, or medical devices work at the molecular or cellular level without overwhelming them. 

By using colorful, illustrative diagrams and dynamic visual cues, these videos break down complex processes, such as drug binding, receptor activation, or enzyme inhibition, into easily digestible steps. While they might lack the depth of 3D visuals, their simplicity makes them ideal for audiences who prioritize context or emotional resonance. 

Take a look at the video below to see how 2D animation visualizes the MOA of Sulfonylureas and Meglitinide Analogs:

Pros:

• Visually engaging: The colorful and dynamic animations create an engaging viewing experience, grabbing the audience’s attention.
• Clear and flexible storytelling: Allows for creative ways to visualize complex processes by incorporating characters and narratives.
• The balance between simplicity and creativity: The style can be customized to align with a company’s branding, colors, and visual identity, enhancing recognition.

Cons:

• Limited depth: The 2D format may not be sufficient to illustrate highly intricate, three-dimensional processes or molecular interactions, resulting in a superficial grasp of complex topics.
• Lack of realism: Complex biological processes may be overly simplified, potentially leading to misunderstandings about how these processes actually work.

Pro tip: If delivered digitally, consider adding interactivity, such as clickable elements or quizzes, to enhance engagement and comprehension.

Now let’s explore 3 MOA videos that use 2D animation to communicate medication administration and pharmacology in an engaging way:

Medication Administration | Name, Class, Mech of Action, Indications, Side Effects

Designed for nurses who are preparing for the NCLEX exam, this video produced by F. Learning Studio introduces the “Fab Five,” which are five essential components that should be included on drug cards, including mech of action. 

The MOA definition is explained briefly but effectively by combining text on the screen and the narration. However, what helps the audience of Simple Nursing grasp the knowledge better is the incorporation of examples and illustrations of how penicillin works to break bacterial cell walls. 

Pharmacological Actions of Adrenergic Drugs

The video below ​​provides an in-depth exploration of how adrenergic drugs, particularly adrenaline, affect various physiological systems. Texts, illustrations, and mind maps are combined seamlessly to introduce the pharmacological actions of adrenergic drugs.  

Local Anesthetics – Mechanism, Indications & Side Effects

Looking for an educational overview of local anesthetics, their mechanisms of action, and their clinical applications? This video covers it all. It features a simple style to create an informative experience that enhances understanding of local anesthetics and their clinical implications.

Whiteboard MOA videos

Whiteboard MOA videos are a creative yet straightforward way to break down complex medical science into digestible insights. These animations mimic the experience of watching an expert sketch out molecular or biological processes in real-time, often featuring hand-drawn visuals and engaging voiceovers. The result is a clear and compelling narrative that simplifies even the most intricate mechanisms of action. 

Their informal and approachable style makes them ideal for early-stage pharmaceutical communication, where the goal is to educate and engage diverse audiences without the need for flashy graphics or high production costs.

To see how whiteboard MOA videos simplify complex science, here’s an example showcasing the mechanisms of action of BCR signaling inhibitors:

Pros:

• Cost-effective production: Whiteboard animations are typically less expensive to produce compared to 3D or high-end animations, especially if kept simple.
• Engaging and familiar format: It creates a sense of intimacy and simplicity by featuring a format that mimics the experience of a live drawing session. The simplicity of the whiteboard format allows audiences to focus on the content without distractions
• Versatile for different audiences: Suitable for a wide range of viewers, from healthcare professionals to patients, as the simplicity can be adjusted to match the audience’s level.

Cons:

• Limited complexity in visuals: Illustrative styles may struggle to effectively convey highly intricate biological processes or interactions, which may require motion or a 3D perspective
• Overuse reduces impact: Whiteboard animations are widely used, and viewers may perceive them as generic or outdated, reducing their ability to engage and convey a unique message.

Pro tip: Use a color palette that is consistent with the drug’s branding to ensure immediate recognition and avoid a generic look.

Below are 3 videos using a clean and engaging visual style of whiteboard animation to enhance understanding and retention of complex pharmacological concepts.

Mechanisms of Action of Anti-CD20 Agents

The use of whiteboard animation is effective in this video creating a clean and focused visual environment to explain the pharmacological mechanisms behind anti-CD20 therapies used in treating chronic lymphocytic leukemia (CLL). It also ​​includes diagrams illustrating key concepts such as the mechanisms of action for CDC and ADCC, making them easier to understand for viewers who may not have a strong background in immunology or oncology.

The function of abatacept

The simplicity of whiteboard animation allows viewers to concentrate on the key information of how abatacept functions in the treatment of autoimmune conditions by inhibiting specific immune responses. Plus, the video shows real-world applications of abatacept in treating autoimmune conditions to prepare healthcare professionals for clinical practice.

How do monoclonal antibodies work? Rituximab, infliximab, adalimumab and others

The video utilizes a whiteboard animation style that is engaging and visually appealing to explain ​​how various monoclonal antibodies function in treating different medical conditions. The narration is clear, concise, and engaging, effectively guiding viewers through complex topics like monoclonal antibodies, and neutralization of toxins while maintaining interest. 

How to Choose the Right Style for MOA Videos

Choosing the right style isn’t just about picking what’s visually appealing; it’s about aligning the video with the audience and considering your time and budget. Here are a few key things you should keep in mind to make the best choice for your MOA videos.

Define the purpose of the video

Ask yourself: Is your video to educate the masses? Raise awareness? Or possibly convince stakeholders? If your goal is to provide technical, in-depth education for professionals or scientists, a 3D video allows you to get granular without sacrificing accuracy. 

But if you want to evoke emotions, build brand recognition, or quickly convey a product’s value, a 2D animation or whiteboard video will be more effective, delivering your message with impact and accessibility.

Understand the target audience

This is about diving deep into the mindset of your audience. Healthcare professionals or researchers often appreciate the precision and complexity of 3D animations that capture intricate molecular processes. However, patients or general audiences may feel overwhelmed by this level of detail. For them, simpler and more relatable options like 2D animations or whiteboard videos could be more effective in keeping them engaged and educated.

3D animations suit professionals, while 2D and whiteboard videos engage patients

Read more: 8 Strategies on How to Improve Patient Education

Consider the complexity of the MOA

The complexity of the drug’s mechanism plays a critical role. If your drug’s MOA involves sophisticated, microscopic interactions—think enzymes, receptors, and cellular processes—a 3D video can provide the depth and clarity needed to show every minute detail with stunning realism. For less complex concepts or for those looking to convey a higher-level message without delving into specifics, 2D or motion graphics might be a smarter choice. 

Read more: 2D vs 3D Animation: Discovering 10 Key Differences 

Examine budget and resources

When choosing an animation style for your MOA videos, it’s important to consider both your visual needs and your budget. Here’s a breakdown of common options to help you decide:

• 3D animations: $12,000 to $80,000+ due to complexity.
• 2D animations: $4,000 to $25,000, ideal for tighter budgets.
• Whiteboard animations: $1,000 to $5,000, perfect for simplified messaging.

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Challenges in MOA Video Production and Their Solutions

Creating the perfect MOA video comes with its share of challenges. From ensuring scientific accuracy to making sure your video remains clear and engaging, the process requires lots of expertise and careful consideration. But don’t worry, we’ve got you covered. This section highlights common obstacles in MOA video production and shares solutions that can streamline the process.

Ensuring scientific accuracy

The complexity of medical science leaves no room for error, as inaccuracies can harm credibility and trust. To overcome this, work closely with subject matter experts to validate every aspect of the video. Cross-check scripts and visuals against peer-reviewed research or established medical guidelines to ensure precision and reliability.

Simplifying complex concepts

Breaking down intricate biological or chemical processes is challenging because these mechanisms often involve multiple steps, specialized terminology, and interactions at a microscopic level. Using storytelling techniques and visual metaphors that distill complexity into relatable visuals is an effective way to simplify complex concepts. 

For example, in the video below, F. Learning Studio uses storytelling with humor, metaphors, and clear keywords to emphasize the key functions of Heparin and Warfarin. For example, comparing anticoagulants to slowing down a “silky smooth river flow” visually explains their role in preventing new clots and the growth of existing ones. This makes challenging concepts easy to understand to the audience, increases engagement, and boosts knowledge retention significantly. 

Balancing creativity and clarity

If an MOA video lacks creativity, it risks being dull and failing to capture the viewer’s attention. On the other hand, if it’s too creative and visually overwhelming, the scientific message can become confusing or unclear. To strike the balance, you should focus on clean, purposeful visuals and highlight critical steps with deliberate pacing, contrasting colors, and concise on-screen text to maintain viewer focus.

High production costs

Producing high-quality MOA videos can be expensive, especially when aiming for detailed 3D animations. Optimize your budget by identifying core visual elements essential to your narrative, using pre-designed assets, while reserving custom ones for pivotal moments. 

At F. Learning Studio, we leverage a versatile animation-style library and bespoke designs to make your MOA video stand out without compromising quality. We combine creativity with precision, ensuring every second of animation captures your audience’s attention while staying true to the science. Contact us to discover cost-effective solutions for your MOA content!

Adapting to diverse audiences

Different audiences have distinct needs—patients may require simplified visuals, while healthcare professionals need technical depth. That’s why you should tailor the level of detail, language, and visual style to suit the target demographic. For instance, patient-focused videos may use vibrant, empathetic visuals, while professional ones focus on precise molecular animations and clinical terminology.

Read more: ​​Addressing Patients’ Unmet Needs: Enhancing Access to Healthcare

Top 5 MOA Video Production Software

Creating effective MOA videos demands the right tools. Selecting the optimal software can significantly impact the quality, efficiency, and overall impact of your videos. By choosing software that aligns with your specific needs and skill level, you can streamline your workflow, enhance creativity, and deliver compelling visual content. Below are our top picks of MOA video software to help you find the best fit for your needs.

Software	Description	Pros	Cons
1. Autodesk Maya	Industry-standard 3D modeling, animation, and rendering software.	High-quality 3D visuals, advanced tools for simulation, strong industry support.	Steep learning curve, expensive licensing costs.
2. Blender	Open-source 3D modeling and animation software with robust features for rendering and simulations.	Free to use, active community, highly customizable, and offers powerful features.	Complex interface, requires plugins for advanced rendering workflows.
3. Moho	Specialized for 2D animation with vector-based drawing tools and bone rigging for character animation.	Easy to use for 2D animations, excellent rigging features, affordable pricing.	Limited 3D capabilities, less suitable for high-end visuals in MOA animations.
4. Adobe After Effects	Motion graphics and visual effects software ideal for creating 2D MOA videos with dynamic storytelling.	Broad integration with Adobe Suite, versatile motion graphics tools, and a user-friendly interface.	Limited 3D capabilities, subscription-based pricing.
5. Renderforest	Cloud-based animation and video creation platform with templates for MOA videos.	Quick and easy to use, affordable for basic animations, no need for advanced skills.	Limited customization, less suitable for intricate or high-quality animations.
6. Cinema 4D	Comprehensive 3D animation and rendering software with a focus on user-friendly workflows.	Intuitive interface, excellent motion graphics tools, strong rendering capabilities.	High cost, fewer plugins compared to other professional 3D software.

However, for those without prior experience in animation, making MOA videos can be tough for beginners in animation due to the steep learning curve and the challenge of creating realistic, scientifically accurate animations. Without the right expertise, it’s easy to lose hours wrestling with complex software or end up with visuals that don’t do justice to your science. 

That’s when F. Learning Studio comes to help. With years of experience working with healthcare organizations, we will help you turn intricate scientific concepts into stunning, easy-to-understand animations. Check out our portfolio to see how we can create a big impact on your next MOA projects. 

Top 5 MOA Video Providers for Your Next Project

When it’s time to bring in the experts, choosing the right MOA video provider is crucial to achieving your desired outcome. Below are the top 5 companies that can help bring your next MOA video project to life, ensuring it meets your needs and budget.

1. F. Learning Studio

With over 8 years of experience in creating different types of 2D medical animated videos, including MOA videos, here are 3 reasons why F. Learning is your ideal partner to bridge the gap between ​​complex scientific information and audience comprehension:

Affordable partner for MOA video production

If your concern is the high cost of MOA video production, then you come to the right place. F. Learning Studio delivers high-quality medical animations at a cost that’s up to 30% less than US-based companies. 

But here’s the thing: the true value of working with us isn’t just in the cost savings – it’s in the impact our animations have on your audience. We take the time to understand your specific needs and goals, then craft a custom animation solution that fits within your budget, ensuring high-quality visuals that deliver results.

Expert at simplifying MOA concepts 

With our extensive experience in the medical field, including collaborations with leading organizations and universities like Simple Nursing and Stanford, we save you time and effort in explaining intricate medical knowledge. 

We don’t just animate these concepts with high accuracy; we also tailor them to resonate with different audiences, ensuring clarity and engagement. Whether you’re targeting healthcare professionals or patients, we customize each animation to communicate effectively and make your message stand out. 

Efficient and streamlined workflow

At F. Learning Studio, we prioritize efficiency and a streamlined workflow to ensure that your project moves forward without unnecessary delays. Our process is designed for smooth communication and minimal back-and-forth, so you can expect your video series to be delivered on time and to the highest standard.

Are you ready to take your medical content to the next level? F. Learning Studio offers the expertise you need to turn your ideas into dynamic, educational animations. Reach out now and let’s craft something extraordinary together.

• WhatsApp: (+84) 378 713 132
• Email: [email protected]
• Fanpage: https://www.facebook.com/f.learningstudio
• LinkedIn: ​https://www.linkedin.com/company/f-learning-studio/​

2. XVIVO Scientific Animation

XVIVO Scientific Animation is a prominent American animation studio based in Hartford, Connecticut, specializing in scientific and medical animations. Founded in 2001, they aim to enhance understanding of intricate biological processes and medical concepts through high-quality animations. Their work is particularly valuable in educational settings, pharmaceutical marketing, and medical communications.

Contact:

• Website: xvivo.com
• Phone: +1 (860) 721-9848
• Address: 915 Silas Deane Highway, Wethersfield, CT 06109, USA

3. Idea Rocket

IdeaRocket specializes in creating high-quality animated videos for various industries, including healthcare, technology, and corporate communications. They offer ​ concept-to-delivery production services for creating Mechanism of Action (MOA) videos and other types of animations. Their services include script writing, design and animation, voice casting and recording, sound design, and final editing.

Contact:

• Website: idearocketanimation.com
• Phone: +1 (646) 504-8300
• Address: 30 East 29th Street, 5th Floor, New York, NY 10016, USA

4. Microverse Studio

Microverse Studios is a specialized 3D animation studio based in Ponte Vedra, Florida, that focuses on creating high-quality scientific and medical animations. They offer comprehensive MOA video production services that encompass every aspect of animation development, including concept development, storyboarding, music, narration, animation, and editing.

Contact:

• Website: microversestudios.com
• Phone: +1 (410) 279-2603
• Address: 140 Pinewoods Street, Ponte Vedra, Florida 32081, USA

5. Random42 Scientific Communication

​​Random42 Scientific Communication is a leading scientific animation studio based in London. Their 3D pharmaceutical animation supports ​​medical education, product launches, corporate communications, patient education, and other marketing and disease awareness initiatives.

Contact:

• Website: random42.com 
• Phone: +44 (0)20 7734 6001
• Address: 51 Great Marlborough Street, 3rd Floor, London W1F 7JT, United Kingdom

Conclusion

MOA videos take complex medical concepts and make them easy to understand, engaging, and memorable. At F. Learning Studio, we focus on delivering MOA animations that are both visually engaging and scientifically accurate. Book a FREE consultation to discover how to do this, and we can create something that will stand out together.

• WhatsApp: (+84) 378 713 132
• Email: [email protected]
• Fanpage: https://www.facebook.com/f.learningstudio
• LinkedIn: ​https://www.linkedin.com/company/f-learning-studio/​

Read more:

• Pharmaceutical explainer videos: Drug MOA animation for dummies
• Top 5 animation studios for pharmaceutical explainer video
• How much does a pharmaceutical explainer video cost per minute?: $100; $1,000; $8,000